MitoProximal Protein Database

Welcome to the MitoProximal Protein Database!

This database is a resource aimed at enhancing the understanding of mitochondrial diseases and metabolic pathways. Jessica L. Fetterman, PhD and Dmitriy Leyfer, PhD employed a computational approach to identify a list of mitochondrial proteins, expanding Mitocarta to include additional proteins related to mitochondrial function. They identified 2059 MitoProximal proteins: nuclear genes identified to be related to mitochondrial function. For more information please refer to the original publication here.

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Help Page

Help Page

The search box in the main search page allows for search strings matching Ensembl Protein ID, gene name, or protein name.

For example, the same result will be returned if you search on “CYC1” (gene name), “cytochrome c1” (protein name), or “ENSP00000317159” (Ensembl Protein ID).

Access advanced search by clicking the grey advanced search button below the search box.

The advanced search function allows the user to control the output and include additional results. These include ...

Data filtering features:

  • Chromosome allows for search of a single chromosome of interest.
  • Data source allows for filtering of genes determined by both studies or by only a single study.

Result filtering features:

  • Show desired columns of data table output by selecting or deselecting checkboxes with column names (Ensembl Protein ID, Protein Name, Chromosome, etc.)
  • Source: show only proteins derived from Mitocarta study or Mitoproximal study
  • Use checkboxes to include additional data associated from Mitocarta (Include Mitocarta Data) or Mitoproximal (Include Hypergeometric Test Results)

The download function is accessed by clicking the grey download button under the search bar. You may select columns to download if you only want specific columns from your results table and select the “Download Selected” radio button or you can click the “Download All” button to download the full table of results. Use the drop-down menu to specify the file type you want to download and click download.

Ensembl IDs in table outputs link to the Ensembl database for more information about your protein(s) of interest.